Preston joined Metacrine as our President and Chief Executive Officer in June 2020. Prior to Metacrine, he was Executive Vice President, Head of Research and Development at Arena Pharmaceuticals, where he oversaw development of multiple early and late-stage clinical programs and contributed to its successful corporate transformation over the past few years. Before Arena, he served as Chief Medical Officer of Laboratoris Sanifit S.L., a biotechnology company, and prior to that was Executive Vice President, Head of Global Development at Orexigen Therapeutics, Inc. Earlier in his career, Dr. Klassen held several positions of increasing responsibility at Amgen Inc., including Therapeutic Area Head for Nephrology. Prior to joining Amgen, he was a faculty member in the Division of Nephrology at Duke University Medical Center. Dr. Klassen received his M.D. from the University of Nebraska College of Medicine and completed his residency in internal medicine, fellowship in nephrology, and masters in health sciences degree at Duke University.